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Metoclopramide otc (Sigma). (6) Injection. Intravenous injection of a total 400 μg/kg/day psilocybin. (7) Placebo or a single 300-mg dose of psilocybin. The two psilocybin experiments were similar to all those in which rats were fed on standard rat chow, except that the psilocybin dose was much higher. In the two psilocybin sessions, 5 d of treatment were used to establish the dose/response curves. It was predicted that the peak experience would fall somewhere in the range from 30 to 70 mg/kg body weight (30-240 mg/m2), but as there are few rats in this range of body weights (e.g., the average weight of 200 or higher is 4–8% of the body weight average rat, and only a few of such rats are used in studies), and as the range has been widely used for other psychedelic agents and drugs in which the peak-expansion occurs this range, peak experiences were determined to occur somewhere in the range from 1 to 5 mg/kg body weight. The psilocybin studies were approved by the Institutional Review Boards of California Institute Integral Studies at San Francisco (12), and the University of Texas Medical Branch at Galveston (18) using protocols that complied with the recommendations of Committee on use Animals in Experiments metoclopramide over the counter alternative (CUEA), an advisory committee to the National Institutes of Health regarding the ethical use of laboratory animals. Materials, how much does metoclopramide tablets cost methods, and analyses In a separate experiment, rats for this study were provided the psilocybin session for 3 d (Fig. 1A). Rats had the opportunity to consume food ad libitum on the morning of third day. Psilocybin The liquid suspension of psilocybin used is available from Travistem (Rome, Italy), which has been synthesized by Terence Kealey (Oxford University, England); his patent (WO201402460) is held by WO Pharma. This is dissolved in a saline solution or is mixed with a food-grade food. All the preparations are freeze-dried during their manufacture and stored in the freezer. preparation is stored in a sterile container before use. In fact, the first use of this drug is often postponed due to freezing problems. The dose of psilocybin available was 300 μg/kg body weight (equivalent to 1,400 μg, 5 mg/kg body weight). There is no information on this dose in the literature, except for an unpublished study which used 1.5 × 2.5 mg/kg body weight and did not obtain full clearance. T